Important information
● Rosuvastatin may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use rosuvastatin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
● Rosuvastatin may cause liver problems. Rarely, severe and sometimes fatal liver failure has been reported in patients taking rosuvastatin. Your risk of developing liver problems may be greater if you drink alcohol daily or in large amounts with rosuvastatin, or if you have a history of liver problems. Check with your doctor before drinking alcohol while you are taking rosuvastatin. Tell your doctor right away if you experience symptoms of liver problems (eg, yellowing of the skin or eyes; dark urine; pale stools; severe or persistent nausea, loss of appetite, or stomach pain; unusual tiredness).
● Follow the diet and exercise program given to you by your health care provider.
● Tell your doctor or dentist that you take rosuvastatin before you receive any medical or dental care, emergency care, or surgery.
● Women who may become pregnant should use effective birth control while taking rosuvastatin. Check with your doctor if you have questions about using birth control.
● Muscle problems (myopathy) may occur with rosuvastatin. The risk of muscle problems may be greater in people who take higher doses of rosuvastatin, in people 65 years old and older, or in people who have liver or kidney problems or low thyroid function. It may also be greater in those who take it with certain other medicines (eg, niacin). Report any unexplained muscle pain, tenderness, or weakness to your doctor right away, especially if you also have a fever or general body discomfort or if you have muscle problems that persist even after your doctor has told you to stop taking rosuvastatin.
● Diabetes patients - Rosuvastatin may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
● Lab tests, including blood cholesterol levels, liver function, kidney function, and CPK blood levels, may be performed while you use rosuvastatin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
● Use rosuvastatin with caution in ASIAN patients and in the ELDERLY; they may be more sensitive to its effects, especially serious muscle problems (eg, muscle pain, tenderness, or weakness).
● Rosuvastatin should be used with extreme caution in CHILDREN younger than 10 years old; safety and effectiveness in these children have not been confirmed.
● PREGNANCY and BREAST-FEEDING: Do not use rosuvastatin if you are pregnant. It may cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if this medicine is found in breast milk. Do not breast-feed while taking rosuvastatin.
● All medicines may cause side effects, but many people have no, or minor, side effects.
Some medical conditions may interact with rosuvastatin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you .
● If you are pregnant, if you are planning to become pregnant, or are breast-feeding
● if you are able to become pregnant
● if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
● if you have allergies to medicines, foods, or other substances
● if you have a history of muscle problems (eg, pain, weakness), including muscle problems with the use of another statin or a family history of hereditary muscle problems
● if you have low blood pressure, a serious infection, kidney problems, liver problems, thyroid problems, diabetes or high blood sugar levels, or a history of seizures
● if you are dehydrated; have increased creatine phosphokinase (CPK) blood levels; or have metabolism, hormonal, or electrolyte problems
● if you are on dialysis
● if you drink alcohol or have a history of alcohol abuse
● if you have had an organ transplant or have recently had major surgery or a serious injury
● if you do excessive physical exercise
Some MEDICINES MAY INTERACT with rosuvastatin.
● Colchicine, cyclosporine, daptomycin, fibrates (eg, clofibrate, fenofibrate, gemfibrozil), HIV protease inhibitors (eg, atazanavir, lopinavir, ritonavir), or niacin because they may increase the risk of muscle or kidney problems.
● Dronedarone, eltrombopag, or itraconazole because they may increase the risk of rosuvastatin's side effects.
● Colchicine, Anticoagulants (eg, warfarin), cimetidine, ketoconazole, sirolimus, spironolactone, or tacrolimus because the risk of their side effects may be increased by rosuvastatin.
● This may not be a complete list of all interactions that may occur. Ask your health care provider if rosuvastatin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
● Use rosuvastatin as directed by your doctor. Check the label on the medicine for exact dosing instructions.
● An extra patient leaflet is available with rosuvastatin. Talk to your pharmacist if you have questions about this information.
● Take rosuvastatin by mouth with or without food.
● Swallow the tablets whole..
● If you also take an antacid that has aluminum or magnesium in it, take it at least 2 hours after taking rosuvastatin. Check with your doctor if you have any questions.
● Taking rosuvastatin at the same time each day will help you remember to take it.
● Continue to take rosuvastatin even if you feel well. Do not miss any doses.
● If you miss a dose of rosuvastatin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once or within 12 hours of each other.
● Ask your health care provider any questions you may have about how to use rosuvastatin.
● You are allergic to any ingredient in rosuvastatin.
● You have active liver disease or unexplained abnormal liver function tests.
● you are pregnant, think you may be pregnant, may become pregnant, or are breast-feeding.
● Contact your doctor or health care provider right away if any of these apply to you.
Constipation; headache; nausea; stomach pain; weakness.
Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody or dark urine; change in the amount of urine produced; chest pain; confusion; depression; joint pain; memory problems (eg, forgetfulness, memory loss); muscle pain, tenderness, or weakness (with or without fever or fatigue); red, swollen, blistered, or peeling skin; severe or persistent headache; severe or persistent nausea or vomiting; severe stomach or back pain (with or without nausea or vomiting); swelling of the hands, ankles, or feet; symptoms of liver problems (eg, yellowing of the skin or eyes, dark urine, pale stools, loss of appetite, unusual tiredness); trouble sleeping.